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Bioinformatics Software Examination Model Paper Examination Methodology
         

SUBJECT: BIO-PROGRAMMING

BIO-PERL

Multiple Choice Question

Q.1 Perl stands for

  • Practical Examination and Report Language
  • Practical Examination and Real Language
  • Practical Extraction and Report Language
  • Practical Extraction and Real Language

Ans. c

Q.2 Perl is invented by

  • Larry Naughton
  • Larry Wall
  • Bill John
  • Ken Thompson

Ans. b

Short Question Answer

Q.3 Who was the creator of Perl?

Ans. Larry Wall.

Q.4 Why are comments important to Programming?

Ans. Comments will enable you to figure out the intent behind the mechanics of your program.

 

C++

Multiple Choice Question

Q.1 OOP stands for

  • Object-oriented project
  • Object-oriented program
  • Object-oriented programming
  • Object-oriented pattern

Ans. c

Q.2 ADT stands for

  • Abstract data Tools
  • Abstract data Types
  • Abstract data Transform
  • Abstract data Time

Ans. b

Short Question Answer

Q.1 What does the following preprocessor directive do?

#include<iostream.h>

Ans. #include<iostream.h> is called a preprocessor directives.

The preprocessor directive #include tells the compiler to insert another file into the source file. Here the preprocessor directive #include tells the compiler to add the source file iostream.h to the program file before compilation.

Q.2 What statement would you use to print the phrase "Hello, world" and then start a new line?

Ans. cout<<"Hello, world\n";

 

BIO-JAVA

Multiple Choice Question

Q.1 JVM stands for

  • Java Vital machine
  • Java Virtual machine
  • Java Virus machine
  • Java Virtuals machine

Ans. b

Q.2 Which one is an interpreter for bytecode?

  • JVM
  • JIT
  • JNI
  • JAVA

Ans. a

SUBJECT: BIOLOGICAL DATABASE & THEIR MGMT.

A. SQL (Structured query Language)

Multiple Choice

1. SQL is the combination of

i) DDL and DQL

ii) DDL , DML and DQL

iii) DDL,DML,DQL and DCL

iv) None of these

2. How many types of Database Management System available

i) One type

ii) Two type

iii) Three type

iv) None of the above

 

 

 

 

B. Biological Database Question

Multiple choice

1. Purposes of Biological Databases

i) Data Mining

ii) References of literature

iii) Cross references

iv) All of the above

2. NCBI Database V consists of

i) COGS

ii) Entrez

iii) SAGE

iv) DbSTS

C. State whether the given statement is True or False

1. Biodiversity is a measure of the variety of the Earth's animal, Plants and Microbial species.

[ ]

2. TrEMBL is a Computer-annotated supplement of SWISS-PROT that contains all the translations of EMBL nucleotide sequence entries not yet integrated in SWISS-PROT. [ ]

Answer

A. SQL (Structured query Language)

1. iii, 2. iii

B. Biological Database

1. iv, 2. i, ii

C. True or False

1. True, 2. True

 

SUBJECT: MICROBIOLOGY

Multiple Choice Question

 

Q.1. The microbes play an important role in the catalytic complicated chemical reactions of

    1. Wine productions

    2. fermentation

    3. dairy product

    4. all of the above

Ans. (d)

Q.2. Bacteria are present every where except in

(a) ice (b) soil

(c) sea water (d) Distilled water

Ans. (d)

Q.3. Microbiology is a discipline of science dealing with the study of ........

a) Forms and structure of organism

b) Malignant tissues

c) Microbes

d) Parasites

Ans. c

Q.4. Fill in the blanks

Pencillin was discovered and discribed by .................. .

Ans. Alexander fleming

Q.5. True / False

Chemoautotrophs bacteria can grow in inorganic medium in the absence of light.

Ans. True

SUBJECT: BIOCHEMISTRY

Multiple Choice Question

Q.1 The unique properties of each amino acid are determined by its particular -

a) R-groups

b) H-bonds

c) Peptide

d) Amino groups

Ans. a.

 

Q.2. Who introduced the term Biochemistry

  1. Marshall Nirenberg

  2. Carl Neuberg

  3. John H. Northrop & Kunitz

  4. Van Helmont

    5. Ans. (b)

    Q.3 Fill in the blanks

    The proteins are made up of linear chain of ................. linked by ........... linkage.

    Ans. Amino acid, peptide

    Q.4 True / False

    Insulin controls the release of free fatty acids from adipose tissue.

    Ans. True.

     

    Q.5. Optical isomerism arises from the presence of

    (a) an asymmetric carbon atom (b) a center of symmetry

    (c) a line of symmetry (d) None

    Ans. (a)

     

     

     

    SUBJECT: METABOLIC CONCEPTS

     

    Multiple Choice Question

    Q.1 Alanine is found in-

    a) Skin

    b) Muscles

    c) Brain

    d) all of the above

    Ans. b

     

    Q.2 Fill in the blanks

    Pyruvate is used to produce ................. .

    Ans. Glucose

    Q.3 True / False

    In the conversion of pyruvic acid to acetyl co-enzyme A, NAD+ is reduced.

    Ans. True

     

    Multiple Choice Questions

    Q.4. In the breakdown of glucose to pyruvic acid, how many enzymes catalyze this successive steps

  5. 3

  6. 6

  7. 9

  8. 10

Ans. (d)

Q.5. During catabolism, glucose is converted to G.6.P. using A.T.P., while in anabolism

    1. glucose is formed from phosphate ester by hydrolysis.

    2. glucose is formed from pyruvate

    3. Pyruvate is produced from its enol phosphate by transphosphorylation to ADP

    4. None of these

Ans. (a)

Fill in the Blanks :

  1. Enthalpy of a compound is equal to its __________. (heat of formation).

  2. An endothermic reaction is one in which heat is __________. (absorbed)

 

 

SUBJECT: VIROLOGY

Multiple Choice Questions

  1. Which among the following contains only one type of nucleic acid
  1. Bacteria
  2. Virus
  3. Dead virus
  4. All

Ans. (b)

  1. The plant virus was first isolated in crystalline form
  1. TMV
  2. Bacteriophages
  3. Cyanophages
  4. None of these.

Ans. (a)

Fill in the Blanks

  1. DNA viruses of eukaryotic cells may have originated from the functional DNA of cellular organelles like ........... and ........... rather than for nuclear DNA.

Ans. (mitochondria, chloroplast)

True or False

4. Ca+2 ions play a vital role in the stabilization of both elongated and spherical plant viruses.

Ans. (T)

5. Most of the plant viruses have multipartite RNA.

Ans. (F)

 

SUBJECT: GENETIC ENGINEERING

CHOOSE THE MOST SUITABLE OPTION:

  1. Manipulation of the genetic material towards a desired end in a directed & predetermined way is called
  1. Genetic engineering
  2. Gene cloning
  3. Recombinant DNA technology
  4. All of the above

Ans:d.

  1. The molecular scissors used to cut DNA into specific genes of interest are called
  1. Exonucleases
  2. Restriction Endonucleases
  3. Ligases
  4. Polymerases

Ans:b.

COMPLETE THE FOLLOWING STATEMENTS:

  1. The enzymes possessing the identical recognition sites are known as ______________________(isoschizomers)

MARK (T) FOR TRUE & (F) FOR THE FALSE STATEMENTS:

  1. Reaction temperature & ionic concentration are the important parameters which influence ligase reactions.(T)
  2. Prokaryotic DNA polymeraseII can use nicked duplexes like DNA polymeraseI.(F)

 

SUBJECT: IMMUNOLOGY

CHOOSE THE MOST SUITABLE OPTION:

  1. A set of disease resistance mechanisms that are not specific to a particular pathogen comes under

  1. Adaptive immunity
  2. Innate immunity
  3. Passive immunity
  4. Active immunity

Ans:b.

  1. Which of these is/are the characteristic/s of the specific immunity
  1. Antigenic specificity
  2. Diversity & self\nonself recognition
  3. Immunologic memory
  4. All of the above

Ans:d.

 

COMPLETE THE FOLLOWING STATEMENTS:

  1. The antibodies derived from a single clone and specific for a single epitope are known as____________________________(Monoclonal antibodies)

 

MARK (T) FOR TRUE & (F) FOR THE FALSE STATEMENTS:

  1. HAT medium contains aminopterin to block the salvage pathway & hypoxanthine and thymine to allow growth by the de novo pathway.(F)
  2. Exogenous antigen is produced outside the host cell & enters the cell by endocytosis or phagocytosis.(T)

 

SUBJECT: INDUSTRIAL FERMENTATION TECHNOLOGY

CHOOSE THE MOST SUITABLE OPTION:

  1. Microbes have a relatively ______________that allows the chemical conversions possible.

  1. high metabolic rate
  2. large surface area
  3. high multiplication rate
  4. all of the above

Ans: d.

  1. The medium is added continously to the fermentor tank to replace that which has been fermented. This is true in case of
  1. Batch technique
  2. Continous flow technique
  3. Both are true
  4. None is true

Ans:b.

COMPLETE THE FOLLOWING STATEMENTS:

  1. Any aerobic or anaerobic process catalyzed by microbes under controlled conditions is called________________________(fermentation)

MARK (T) FOR TRUE & (F) FOR THE FALSE STATEMENTS:

  1. The spontaneous mutations depend on the growth conditions of the organism (T)
  2. Batch fermentation is considered to be an "open system"(F)

 
SUBECT: MOLECULAR GENETICS

CHOOSE THE MOST SUITABLE OPTION:

  1. Removal of the topological strain by inducing the negative supercoiling is carried out by

  1. Topoisomerases

  2. DNA gyrases

  3. Primases

  4. DNA polymerases

Ans:b.

  1. Chromosomal aberration in which two breaks occur in a chromosome & the intercalary segment reunites in a reverse order is categorised as

  1. Duplication

  2. Deletion

  3. Inversion

  4. Translocation

Ans:c.

 

COMPLETE THE FOLLOWING STATEMENTS:

  1. ABO blood groups is a good example for both ___________ & multiple allelism.(codominance)

 

MARK (T) FOR TRUE & (F) FOR THE FALSE STATEMENTS:

  1. Termination zone is essentially needed for the termination of DNA replication in prokaryotes.(F)

  2. 5 A B C D t DCBA3

3ABCDt D C B A 5

is a palindromic sequence.(T)



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